Harris D, et al. - Researchers developed and sought validation for a frailty-based, procedure-specific risk score for patients undergoing thoracic endovascular aortic repair (TEVAR) for elective thoracic aortic aneurysm (TAA). This study comprised derivation or validation cohorts of patients undergoing nonemergent TEVAR for TAA during 2005 to 2016 in the National Surgical Quality Improvement Program database. Markers of frailty and procedure extent were found to be strong predictors of major adverse events (MAEs) after TEVAR for TAA, in addition, these could provide an improved patient selection by enabling patient- and procedure-specific risk stratification. In low-risk patients, TEVAR may be safely performed, while careful discussion of the risks and benefits of aortic intervention is justified in intermediate-risk patients; under certain circumstances, high-risk patients may not benefit.