Anna Deminger, et al. - In patients with ankylosing spondylitis (AS), researchers sought to study spinal radiographic progression and assessed factors that could predict progression overall and by sex. As per data, this is the first report on sex-specific predictors of spinal radiographic progression, which suggested the predictors partly differ between the sexes. Obesity in both sexes and exposure to bisphosphonates in women were the new predictors identified. Baseline AS-related spinal radiographic alterations, among previously known predictors, predicted radiographic progression in both sexes. High CRP was the predictor in men (with a trend in women) and smoking was a predictor only in men.