Li Y, Ren J, Li N, et al. - Via performing a systematic review and meta-analysis of RCTs, researchers sought to ascertain how oral dehydroepiandrosterone (DHEA) supplementation affects testosterone levels. Searching Scopus, Embase, Web of Science, and PubMed databases up to February 2020, they identified 42 publications (comprising 55 arms) demonstrating a significant increase in testosterone level after DHEA administration. All subgroups exhibited increased testosterone level in correlation with receiving DHEA, however, females had higher magnitude of increment relative to men; DHEA dosage of ˃ 50 mg/d compared with ≤ 50 mg/d; intervention duration of ≤ 12 weeks compared with ˃ 12 weeks;