Cao B, Gong C, Wu D, et al. - Since obesity was related to many chronic diseases including cortisol rhythm disorder and low testosterone, researchers performed a cross-sectional survey to test the assumption that obese prepubertal boys have higher androgen hormones (FT, DHEA, androstenedione), late pubertal boys have lower androgen hormones concentrations as compared with lean boys. The sample consisted of 1,148 boys, aged 6–14 years, and divided into overweight/obesity (OW/OB) group and normal weight (NW) group. According to Tanner scale and testicular volume, puberty status was assessed. In prepubertal obese vs NW boys, the adrenal androgens DHEA and androstenedione were increased, consistent with the reported increase in premature adrenarche frequency in obese children. Furthermore, the lower androgen levels of OW/OB boys at the late pubertal and postpubertal stages should be given more attention.