Johari HH, et al. - Researchers ascertained the frontal recess anatomy cell variations and its relationship with frontal sinusitis. They also evaluated the incidence of frontal recess cells in the population, the presence of frontal recess cell variations in chronic rhinosinusitis and non-chronic rhinosinusitis and the association of frontal recess cell variation in the development of frontal sinusitis. Malaysian subjects demonstrated the frontal recess cells variation that were almost similar to those reported in other Asian populations such as Japanese, Taiwanese, Chinese and Korean. Findings suggested a significant association of the bullar cells with the development of frontal sinusitis than other frontal recess cells. It was very important to understand the frontal recess anatomical structures as this would lead to a successful treatment of CRS. It also helped the surgeon to have a better plan of endoscopic sinus surgery to prevent the disease recurrence and surgical complication.