Burger JA, Kleeblad LJ, Sierevelt IN, et al. - The intent of this study was to comprehensively assess survivorship of lateral UKA with registry data and compare this to medial unicompartmental knee arthroplasty (UKA). Researchers selected 537 lateral and 19,295 medial UKAs between 2007 and 2017 from the Dutch Arthroplasty Register. The results indicated no significant increased risk for revision for lateral UKA in the multivariable regression analyses. The study noted similar survivorship of lateral and medial UKA. Particularly, the risk was found for revision when using mobile-bearing designs for lateral UKA. It was demonstrated that failure modes and type of revision depends on laterality and bearing design. The data indicate that surgical challenges related to anatomy and kinematics of the lateral and medial knee compartment require to be considered.