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A comparison of three classification criteria sets for systemic lupus erythematosus – A study looking at links to outcome and mortality

Arthritis Care & Research Oct 26, 2019

Carneiro AC, et al. - Using data from 100 individuals, experts contrasted the ability of the American College of Rheumatology (ACR), Systemic Lupus Erythematosus International Collaborating Clinics (SLICC) and European League Against Rheumatism (EULAR)/ACR SLE classification criteria sets in order to give knowledge about organ damage and mortality, over a 10-year follow-up period. A statistically important relationship between the EULAR/ACR set and renal damage and SDI, the latter, following adjustment for age and gender, was found. Higher EULAR/ACR scores were related to greater rates of organ damage in the individuals negative for other autoantibodies. In summary, the data imply that the EULAR/ACR set may give beneficial prognostic knowledge since higher scores were related to greater rates of organ damage. Moreover, in individuals negative for non-diagnostic-SLE autoantibodies, who may profit more from the predictive capacity of the EULAR/ACR set, these findings were more obvious.
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