Celenay ST, et al. - The efficacy of a 6-week combined exercise program with and without connective tissue massage (CTM) on pain, fatigue, sleep problem, health status, and quality of life in patients with fibromyalgia syndrome (FMS) were compared in this study. The outcome of this study proposed that exercises with and without CTM might be successful for decreasing pain, fatigue and sleep problem whereas increasing health status and quality of life in patients with FMS. However, exercises with CTM might be superior in improving pain, fatigue, sleep problem, and role limitations because of physical health compared to exercise alone.