Wilke B, et al. - Investigators assessed 138 candidates to determine the consequence of limb salvage vs amputation for nonmetastatic sarcomas using the Patient-reported Outcomes Measurement Information System (PROMIS). They categorized patients into the limb salvage and amputee cohorts and based on the follow-up (1 to 11 or 12+ months). They estimated 7 PROMIS domains. Higher scores were observed in both the limb salvage group and subjects >12 months from surgery. Improved emotional health was also reported in the limb salvage group vs the US population.