Hong SH, et al. - Whether leukotriene receptor antagonists (LTRAs) vs inhaled corticosteroids (ICSs) are effective in elderly patients with asthma, was investigated in real-world settings. Using the 2003-2010 National Sample Cohort data of Korea, researchers obtained records for elderly patients with asthma who were newly prescribed LTRAs or low-dose ICSs. They compared the 2 groups for asthma exacerbation risk, using Cox proportional-hazard regression following propensity score–based inverse probability of treatment weighting to balance covariates between therapy groups. As far as the risk of asthma exacerbation was concerned, no difference was found between LTRAs and low-dose ICSs in terms of their efficacy when administered to elderly patients with asthma. LTRAs can be thought a reasonable alternative first-line treatment for elderly patients with mild asthma, given the practical advantages obtained from convenient administration.