Wahab RA, et al. - In the present study, researchers compared the observer agreement of microcalcification detection on synthetic 2D images to full field digital mammography (FFDM) at screening as well as tested whether calcifications can be detected to the same degree and given the same BI-RADS assessment. For this investigation, 414 women obtained a screening mammogram with tomosynthesis and acquisition of FFDM between March 2016–December 2016. It was noted that the radiation dose for the combined DBT and FFDM was approximately double the dose of standard FFDM. They found that there was a reduction in 40 to 50% of the radiation dose by eliminating the full field digital mammogram with synthetic 2D imaging. For detection of microcalcifications at screening, FFDM and synthetic 2D mammograms have acceptable observer agreement.