Shapiro JA, et al. - In this study, experts sought to compare the performance characteristics of the high-sensitivity guaiac fecal occult blood test (HS-gFOBT) Hemoccult II SENSA and two fecal immunochemical tests (FITs) (InSure FIT and OC FIT-CHEK) for detecting advanced colorectal neoplasia. They proposed that compared to the HS-gFOBT Hemoccult II SENSA, some FITs were more sensitive, but these results required to be confirmed in larger asymptomatic populations. To determine the best tests for population screening, comparisons between the FITs examined in this study and other FITs were required.