Zhang DY, et al. - Researchers assessed the prognostic significance of masked hypertension and masked uncontrolled hypertension defined by ambulatory or home blood pressure (BP) monitoring, via this comparative meta-analysis of 21 prospective observational studies involving 130,318 patients. The included studies were identified from English literature searched till 2 September 2018. For all-cause mortality (eight studies) and cardiovascular mortality (three studies), a pooled risk ratio of 1.67 and 2.19, respectively, was reported for masked hypertension vs normotension. Also, 1.71, 1.95, 1.76, 1.62, 3.85 pooled risk ratios were reported for fatal and nonfatal cardiovascular (15 studies), stroke (two studies), cardiac (two studies), coronary (two studies) and renal disease events (two studies), respectively, for masked hypertension vs normotension. Irrespective of the out-of-office BP monitoring techniques, unfavorable clinical outcomes were reported in relation to masked hypertension and masked uncontrolled hypertension.