Shi H, et al. - The clinicopathological and molecular characteristics in two pure adenoid basal carcinoma (ABC), 15 squamous cell carcinoma (SCC) with ABC-/adenoid cystic carcinoma (ACC)-like peculiarities and seven basaloid SCCs (BSCCs) by chart review, immunohistochemistry, HPV RNA in-situ hybridization and fluorescence in-situ hybridization were investigated in order to examine the correlation between ABC, ACC and SCC in the uterine cervix. The mixed carcinomas included variable SCCs and ABC-/ACC-like components exhibiting inexplicable transitional zones. All components consistently exhibited diffuse p16, p63 and SOX2, variable cytokeratin (CK)7 and CK17 and rare Ber-EP4 and MYB expression and a substantially lower Ki67 index in pure ABCs and the ABC-like components were noted. No myoepithelial differentiation (SMA, calponin and S100) and MYB gene fusions were presented by the ACC-like components. In BSCCs vs mixed carcinomas, CK7, CK17, and Ber-EP4 were statistically more robust. In 12 mixed carcinomas and seven BSCCs, high-risk HPV (HR-HPV) E6/E7 mRNA was identified, although not in pure ABCs. In the SCC components and BSCCs vs the ABC-like components of mixed carcinomas, the HR-HPV mRNA expression was higher. Hence, in mixed carcinomas, the ACC-like components seemingly present the morphological mimics of salivary ACCs. ABC-like components could be the potential precursor of the ACC-like and SCC components. Moreover, in the pathogenesis of SCCs with ABC-/ACC-like peculiarities, HR-HPV oncogenes could play a role.