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A case-control study of exposure to organophosphate flame retardants and risk of thyroid cancer in women

BMC Cancer Jun 13, 2018

Deziel NC, et al. - Researchers assessed the association between organophosphate flame retardant (PFR) exposure and thyroid cancer. They also investigated if PFR exposure was predicted by individual or temporal factors. The data for 100 incident female, papillary thyroid cancer cases and 100 female controls of a Connecticut-based thyroid cancer case-control study were analyzed. They found no link between urinary PFR concentrations, measured at time of diagnosis, with an increased risk of thyroid cancer. On stratification by microcarcinomas (tumor diameter ≤ 1 cm) and larger tumor sizes (> 1 cm), results remained null. With increasing body mass index and in the summer season, urinary PFR concentrations were higher.

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