Shieh A, Ishii S, Greendale GA, et al. - Formerly obtained bone resorption marker (urine collagen type I N-telopeptide) and femoral neck strength data from 696 individuals from the Study of Women’s Health Across the Nation, a longitudinal study of the menopause transition (MT) in a multi-ethnic cohort of community-dwelling women were pooled in this study in order to evaluate whether a bone resorption marker, measured early in the MT, was related to rates of variation in femoral neck width, compression strength index and impact strength index during the MT. It was discovered that in pre- and early perimenopause, measuring a bone resorption marker could distinguish females who would encounter the highest loss in bone strength during the MT.