Guo X, Li X, Qi T, et al. - Researchers aimed to report on the outcome of preterm births and hospitalized preterm infants by gestational age (GA) in Huai’an in 2015, an emerging prefectural region of China. They identified reporting of a total of 59,245 regional total births. Of these, they retrieved clinical data on 2,651 preterm births and 1,941 hospitalized preterm neonates from Huai’an Women and Children’s Hospital (HWCH) and non-HWCH hospitals in 2018–2020. The prevalence of extreme, very, moderate, late and total preterm of the regional total births were 0.14%, 0.53%, 0.72%, 3.08% and 4.47%, with GA-specific neonatal mortality rates being 44.4%, 15.8%, 3.7%, 1.5% and 4.3%, respectively. Significantly in-hospital death risks were observed for the hospitalized preterm infants, in correlation with out-born of HWCH, GA < 32 weeks, birth weight <  1000 g, Apgar-5 min < 7, birth defects, respiratory distress syndrome, necrotizing enterocolitis and ventilation, whereas decreased death risks were recorded in correlation with born in HWCH, antenatal glucocorticoids, cesarean delivery and surfactant use. As per the integrated data, they described the prevalence, GA-specific morbidity and mortality rate of total preterm births and their hospitalization, illustrating the efficiency of the leading referral center and whole regional perinatal-neonatal network in China.