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A 7-year surveillance of the drug resistance in Klebsiella pneumoniae from a primary healthcare center

Annals of Clinical Microbiology and Antimicrobials Nov 19, 2019

Li G, et al. - Researchers determined resistance rates in Klebsiella pneumoniae strains from primary hospitals, and the resistance distribution among the different isolate sample sources. From patients who visited a primary healthcare center in Central Zhejiang Province from January 2011 to December 2017, isolation of 5,319 K. pneumoniae strains was executed. The resistance rates of K. pneumoniae strains varied from 1.4% (ertapenem) to 23.1% (nitrofurantoin) among the 20 antimicrobial drugs studied; this high variability could be due to the involvement of distinct resistance mechanisms. They identified the highest resistance rates of K. pneumoniae strains to most antibiotics in urine samples. These are partly due to the extended-spectrum β-lactamase, indicating the necessity for providing a special attention in the treatment of urinary tract infection.

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