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A 3-year longitudinal study of skeletal effects and growth in children after kidney transplantation

Pediatric Transplantation Jul 15, 2018

Swolin-Eide D, et al. - In this prospective study, the researchers examined growth and skeletal development for 3 years after kidney transplantation in pediatric patients, 3.4-15.0 years of age. They evaluated growth, BMD, bone resorption markers (CTX and TRACP5b), bone formation markers (PINP, ALP, and osteocalcin), PTH, and vitamin D at the start, 3, 12, and 36 months after transplantation. According to the findings obtained, height SDS and BMI SDS increased, along with the increased formation markers that exhibit a positive bone acquisition after kidney transplantation, which was reflected by the significant increase in total body BMC.
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