Pang H, et al. - Through a prospective cohort study of 37 patients with gliomas from whom 63 biopsy specimens were obtained, the researchers determined the relation between cerebral blood flow (CBF), measured by 3D pseudo-continuous arterial spin-labeling (3D-ASL), and vascular endothelial growth factor (VEGF) expression in gliomas on the basis of coregistered localized biopsy, and examined whether CBF correlated with survival month. For both low-grade glioma and high-grade glioma, CBF-derived 3D-ASL positively and significantly linked with VEGF expression, which is an independent risk factor for overall survival in these patients.