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25-Hydroxyvitamin D concentrations and risk of metabolic syndrome in systemic lupus erythematosus women

International Journal of Rheumatic Diseases Oct 18, 2019

García-Carrasco M, Mendoza-Pinto C, Cabrera-Jiménez M, et al. - In 160 women with SLE and who did not have diabetes, cross-sectional analyses of the association between concentrations of 25-hydroxyvitamin D (25(OH)D), metabolic syndrome (MetS), and its components were done. Seventy-nine women with SLE had MetS. Without adjusting for BMI or smoking, according to rising quartiles of 25(OH)D concentrations, the odds of having MetS declined. When adjusted by age, for the highest vs the lowest quartile of 25(OH)D concentrations, the OR of having MetS was 0.4. The crude OR of having raised hypertriglyceridemia reduced relative to rising quartiles of 25(OH)D concentrations. Nonetheless, additional adjustments for BMI and smoking eliminated the inverse relationship between 25(OH)D concentrations and MetS and its individual elements. Hence, in women with SLE and who did not have diabetes with mild activity, 25(OH)D concentrations were concluded to be not related to MetS and its components.
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