Here is a summary of the latest information on disease progression in patients with COVID-19 who have comorbidities, including timeline of onset of complications and guidance on management of acute respiratory distress syndrome in COVID-19.
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COVID-19 has debilitating impact on patients with comorbidities, but what are the effects of specific comorbidities and related treatment strategies on disease progression? How does COVID-19 progress in patients who develop certain complications such as acute respiratory distress syndrome (ARDS)?
ARDS and COVID-19
In a study published in JAMA, Wu et al examined the risk of patients (N=201) with COVID-19 developing ARDS and clinical outcomes in patients who developed ARDS after hospital admission, and those progressed from ARDS to death (Wu et al, 2020)