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Clinical pearls for heart failure

M3 Global Newsdesk Jun 10, 2021

Here are 30 quick clinical practice points for managing heart failure in the real world. The article lists the most updated research on the disease.


Stay sharp with the latest research in cardiology and heart failure 

  1. Canagliflozin improves outcomes in patients with type 2 diabetes and CKD regardless of the presence of heart failure
  2. Adding ivabradine to standard therapies improves cardiac function in patients with chronic heart failure
  3. Soluble ST2 and catestatin levels predict in-hospital mortality in patients with acute worsening of heart failure
  4. RV strain helps predict outcomes in patients with heart failure and preserved ejection fraction
  5. Lipid profiling may capture preclinical molecular alterations that predispose for incident HF
  6. Ischemic heart disease adversely impacts the clinical course of HFpEF
  7. Catheter ablation of AF improves outcomes in patients with HF
  8. Frailty is highly prevalent in HFrEF
  9. Methamphetamine use is associated with systolic dysfunction
  10. Cardiac fibrosis is increased in heart failure
  11. CHF hospitalisation in patients with AF is a poor prognostic marker
  12. Empagliflozin improves heart failure outcomes across the range of kidney function
  13. Galectin-3 levels are not associated with the risk of incident HF in patients with chronic kidney disease
  14. Heart failure risk from systemic lupus erythematosus is greatest at younger ages
  15. A history of prior MI is tied to a greater risk of CV death in patients with heart failure and preserved ejection fraction
  16. HF risk scores have comparable performance in men and women
  17. Hypothyroidism doesn't affect mortality risk in patients receiving cardiac resynchronisation therapy for heart failure
  18. Failure of noninvasive ventilation increases the risk of in-hospital mortality in patients with acute heart failure
  19. A smoking history worsens CV outcomes in patients with heart failure and reduced, but not preserved, ejection fraction
  20. Sacubitril-valsartan is superior to ACE inhibitors and ARBs for patients with heart failure
  21. LV hypertrophy on ECG predicts heart failure hospitalisation in middle-aged women but not men
  22. The coexistence of multiple frailty domains is common in elderly patients hospitalised with heart failure
  23. Mortality is higher among patients with advanced heart failure living in rural vs urban areas
  24. Soluble ST2 and catestatin levels predict in-hospital mortality in patients with acute worsening of heart failure
  25. RV strain helps predict outcomes in patients with heart failure and preserved ejection fraction
  26. The urinary proteomic classifier HF1 performs as well as BNP for the diagnosis of heart failure
  27. Methotrexate lowers heart failure risk in patients with rheumatoid arthritis
  28. High levels of parathyroid hormone and fibroblast growth factor-23 predict incident heart failure
  29. Statins reduce neurological events in advanced heart failure patients implanted with LV assist systems
  30. A history of prior MI is tied to a greater risk of CV death in patients with heart failure and preserved ejection fraction

This story is contributed by MDLinx Staff and is a part of our Global Content Initiative, where we feature selected stories from our Global network which we believe would be most useful and informative to our doctor members.

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