Study confirms vaginal health benefits of using ultralow dose before and after surgery.
A new study demonstrates how an ultralow dose of vaginal estriol gel used before and after pelvic organ prolapse surgery can improve recovery time and results.

The study outcomes were published online in the journal Menopause.

Postmenopausal women, whose estrogen levels have dropped and vaginal walls have thinned, are more likely to experience pain during the recovery period after surgery and beyond. Topical estrogens, which absorb rapidly through the vaginal wall and thus can be used at low concentrations, have already proven effective in treating a number of vaginal problems commonly associated with menopause. The published data from the study, “Effects of ultralow topical estriol dose on vaginal health and quality of life in postmenopausal women who underwent surgical treatment for pelvic organ prolapse,” suggests that presurgery treatment using 0.005% vaginal estriol gel improved vaginal health and related symptoms in women with pelvic organ prolapse. The use of the vaginal gel after surgery additionally improved recovery times and results.

The Italian–based study included 75 women aged 56 to 63 years who had been menopausal between 7 and 14 years. The authors acknowledged that additional studies are necessary to evaluate the long–term efficacy of the vaginal estriol treatment and verify its extended benefits.

“Postmenopausal women with urogenital atrophy complain of vaginal dryness and often painful sex that improves with the use of low–dose vaginal estrogen, which is available in the United States as a low–dose vaginal cream, tablet, or ring,” says Dr. JoAnn Pinkerton, executive director of NAMS.

“In this study, a vaginal estrogen product that is not available in the United States was tested and shown to improve vaginal health before pelvic floor therapy and to improve sexual health and quality of life if continued after surgery. Another finding was that combining vaginal estrogen with regular sexual activity led to improvement in vaginal health over using vaginal estrogen alone.”