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Treat insomnia before sleep apnea

ScienceDaily Aug 16, 2019

The "double whammy" of co-occurring insomnia and obstructive sleep apnea (OSA) is a complex problem best managed with non-drug targeted psych interventions, a new Australian study has found.

By following simple new guidelines, people with the concurrent conditions reported great improvement to both their sleep and their health, with about 50% improvement in global insomnia severity and night-time insomnia after 6 months.

Co-morbid insomnia and sleep apnea (COMISA) is a little studied and debilitating disorder which can be improved by identifying and treating insomnia separately.

The new Australian study of 145 patients aimed to work out better treatments for COMISA patients who, in the past, have shown poor results from using continuous positive airway pressure (CPAP) therapy, compared to patients who do not report symptoms of insomnia.

As a result, the sleep experts are advising people living with both conditions to be treated first with a targeted, 4–10 week program of cognitive and behavioral therapy for insomnia (CBTi) before using CPAP machines to reduce the effects of sleep apnea.

"We found that treating COMISA patients with non-drug CBTi before commencing CPAP significantly improved insomnia symptoms," says lead researcher Dr. Alexander Sweetman, from the Adelaide Institute for Sleep Health at Flinders University. "Importantly, we also found increased use of CPAP therapy by about 1 hour per night in patients treated with CBTi and CPAP therapy, compared to a group receiving treatment with CPAP alone."

OSA patients—who comprise around 10% of the general population—suffer from frequent airway narrowing events during sleep, which lead to poor quality of sleep and reduced daytime functioning. About one-third of OSA patients also report clinically significant insomnia symptoms, including long-term difficulties falling asleep at the start of the night, or long awakenings during the night.

The study found the new routine resulted in CBTi patients increasing acceptance of CPAP devices by 87% and increased long-term CPAP use by 1 hour each night over the first 4 months. At 6 months, combined CBTi and CPAP therapy led to significant improvements of:

  • 52% in global insomnia severity vs 35% in the control group
  • 48% in night-time insomnia complaints vs 34%
  • 30% in dysfunctional sleep-related cognitions vs 10%

Heart disease, obesity, and depression have been connected to insomnia and sleep apnea, so getting the best therapies are important to health and well-being for millions of people around the world, says co-author professor Doug McEvoy.

"Long-term cardio-metabolic benefits for patients with COMISA is an important consideration, independent of those debilitating symptoms which can be relieved with the right treatment," McEvoy says.

"This latest study suggests that sleep physicians and clinics should screen for insomnia symptoms and, if present, treat the insomnia with CBTi to improve subsequent acceptance and use of CPAP therapy. This will improve outcomes for both disorders."

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