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Quit-smoking drug safe for lung disease patients

University of Edinburgh College of Medicine News May 16, 2017

Medication that helps smokers to quit is safe for use by people with chronic lung conditions, research suggests.

Experts say smokers with smoking–related diseases should be prescribed the drug to stop their illness from progressing.

Doctors have previously been reticent to give the drug to these patients because of reported links to heart disease and depression.

Researchers say they found no evidence of such a link and that concerns are unwarranted.

Varenicline is the most effective medication to help smokers quit, but previous reports have suggested that users may be more likely to suffer a heart attack.

The drug – also known as Champix™ or Chantix™ – has also been linked to depression, self–harm and suicide.

A study of more than 14,000 people with chronic obstructive pulmonary disorder, or COPD, found that those using the drug were no more likely to suffer a heart attack than those using nicotine replacement therapies.

Treatment did not affect their risk of depression or self–harm either, researchers say.

"Varenicline is a highly effective anti–smoking drug so it is reassuring that our findings have confirmed that it is safe for use in patients with COPD," said Professor Aziz Sheikh, Co–Director, the University of Edinburgh’s Centre for Medical Informatics.

The study was published in the journal Thorax.
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