Researchers have uncovered the first scientific evidence of a 'higher' state of consciousness.

In the study, neuroscientists observed a sustained increase in the diversity of brain signals of people under the influence of psychedelic drugs, compared with when they were in a normal ‘awake and aware’ state.

This measure of the complexity of brain activity – called neural signal diversity – provides an index of the level of someone’s consciousness.

Scientists have shown that people who are awake have more diverse neural activity using this scale than those who are asleep. Previous studies have tended to focus on lowered states of consciousness, such as when people are asleep, under anaesthesia, or are in a ‘vegetative’ state.

The researchers say that while further research is needed using more sophisticated and varied models to confirm the results, they are cautiously excited.

“This finding shows that the brain–on–psychedelics behaves very differently from normal,” said Professor Anil Seth, co–director of the Sackler Centre for Consciousness Science at the University of Sussex, who led the research.

“During the psychedelic state, the electrical activity of the brain is less predictable and less ‘integrated’ than during normal conscious wakefulness – as measured by global signal diversity.

“Since this measure has already shown its value as a measure of ‘conscious level’, we can say that the psychedelic state appears as a higher ‘level’ of consciousness than normal, but only with respect to this specific mathematical measure.”

For the study, researchers from the Sackler Centre at Sussex reanalysed data that had previously been collected by Imperial College London and the University of Cardiff in which healthy volunteers were given one of three drugs known to induce a psychedelic state: psilocybin (‘magic mushrooms’), ketamine and LSD.

Using brain imaging technology, they measured the tiny magnetic fields produced in the brain and found that, across all three drugs, the neural signal diversity was reliably higher.

The researchers stress this does not mean that the psychedelic state is a ‘better’ or more desirable state of consciousness, but shows that the psychedelic brain state is distinctive and can be related to other global changes in conscious level (e.g. sleep, anaesthesia) by application of a simple mathematical measure of signal diversity. Dr Robin Carhart–Harris, from the Department of Medicine at Imperial, said: “Rigorous research into psychedelics is gaining increasing attention, not least because of the therapeutic potential that these drugs may have when used sensibly and under medical supervision.

The findings could help inform discussions gathering momentum about the carefully–controlled medical use of such drugs, for example in treating severe depression.

In addition, the study adds to a growing scientific understanding of how conscious level (how conscious one is) and conscious content (what one is conscious of) are related to each other.