As part of its global response to the growing COVID-19 pandemic, the American Heart Association, the world’s leading voluntary organization focused on heart and brain health and research, is committing $2.5 million to research efforts to better understand this unique coronavirus and its interaction with the body’s cardiovascular and cerebrovascular systems.

Specifically, the Association will be offering fast-tracked research grants for short-term projects that can turn around results within 9-12 months to better understand the diagnosis, prevention, treatment, and clinical management of COVID-19 as it relates to heart and brain health. There will also be additional funding made available to the Association’s new Health Technologies & Innovation Strategically Focused Research Centers to develop rapid technology solutions to aid in dealing with the COVID 19 pandemic.

“Approximately 120 million people in the US have one or more cardiovascular diseases, which may place them at higher risk for contracting COVID-19 and experiencing complications of the virus, making it even more critical that we find out all we can about this disease and urgently work on reducing its impact,” said American Heart Association president Robert A. Harrington, MD, FAHA, Arthur L. Bloomfield Professor of Medicine and chair of the department of medicine at Stanford University. “Research is the very foundation of the American Heart Association and, given our global mission, this rapid response grant is an unprecedented but logical move for the organization in these extraordinary times. We are committed to quickly bringing together and supporting some of the brightest minds in research science and clinical care who are shovel-ready with the laboratories, tools and data resources to immediately begin work on addressing this emergent issue.”

COVID-19, like most in the coronavirus family, is primarily a disease of the respiratory system. However, a number of reports from other countries, as well as in the US, have indicated that people with high blood pressure or who have heart disease or survived a stroke may be more vulnerable to its effects, with mortality rates two to three times higher than in the general population. There have been accounts of infected people without underlying complications who are developing deadly arrhythmias from infection and inflammation that damage heart muscle. Additionally, strokes and other brain diseases have been reported in COVID-19 patients in China. These findings may further illustrate a critical relationship between COVID-19 and the cardiovascular and cerebrovascular systems.

Through the COVID-19 and Its Cardiovascular Impact Rapid Response Grant initiative, the Association will fund one national coordinating center along with at least 10 project grants of $100,000 each. Due to the critical need, the application, review and award processes for the grants will be expedited with applications due by April 6, awardees being announced in early May and projects underway by June. Highly impactful, short-term research projects that can be completed within nine months to a year will take precedence.

Supplemental funding grants are also being offered to the Association’s new Health Technologies & Innovation Strategically Focused Research Network centers. Those Centers have just been selected and will be announced soon. This additional funding will be focused on rapid technology solutions that could possibly provide aid for healthcare systems, doctors or care providers, first responders, patients or consumers in dealing with a pandemic crisis. 

“I am extremely proud of the agility of our volunteer leadership and of the staff of the American Heart Association that allows us to pivot so quickly to initiate vital research to find much needed answer in these challenging times,” said American Heart Association CEO Nancy Brown. “What more important work can we do as an organization than activate our trusted platform to provide solutions for this global crisis.”

More information on the grants and instructions for applying can be found here.

The American Heart Association has funded more than $4.6 billion in cardiovascular research since 1949.